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Index > Protein center > Tcf4(Gene name) > Rat
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  • Tcf4 (Gene name),
  • Transcription factor 4 (Protein name ),  ITF2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tcf4(Itf2;Sef2);
    Protein name:
    Transcription factor 4(TCF-4);
    Alternative:
    R8f DNA-binding protein;Immunoglobulin transcription factor 2(ITF-2;RITF-2);SL3-3 enhancer factor 2(SEF-2);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein. Forms homo- or heterooligomers with myogenin. Interacts with HIVEP2. Interacts with NEUROD2.
    Function:
    Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Interacts with the CCAAT displacement protein (CDP2) to bind the tyrosine hydroxylase enhancer.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    589
    Sequence:
    50:
    MTSRDLGSHD | NLSPPFANSR | IQSKTERGSY | SSYGRENVQG | CHQSLLGGDM | 
    100:
    DMGNPGTLSP | TKPGSQYYPY | SSNNARRRPL | HSSTMEVQTK | KVRKVPPGLP | 
    150:
    SSVYAPSAST | ADYNRDSPGY | SSSKPAASTF | SSSFFMQDGH | HSSDPWSSSS | 
    200:
    GMNQPGYGGM | LGNSHIPQSS | SYCSLHPHER | LSYPSHSSAD | INSSLPPMST | 
    250:
    FHRSGTNHYS | TSSCTPPANG | TDSIMANRGT | GAAGSSQTGD | ALGKALASIY | 
    300:
    SPDHTNNSFS | SNPSTPVGSP | PSLSAGTAVW | SRNGGQASSS | PNYEGPLHSL | 
    350:
    QSRIEDRLER | LDDAIHVLRN | HAVGPSTAVP | GGHGDMHGII | GPSHNGAMGS | 
    400:
    LGSGYGTGLL | SANRHSLMVG | AHREDGVALR | GSHSLLPNQV | PVPQLPVQSA | 
    450:
    TSPDLNPPQD | PYRGMPPGLQ | GQSVSSGSSE | IKSDDEGDEN | LQDTKSSEDK | 
    500:
    KLDDDKKDIK | SITRSRSSNN | DDEDLTPEQK | AEREKERRMA | NNARERLRVR | 
    550:
    DINEAFKELG | RMVQLHLKSD | KPQTKLLILH | QAVAVILSLE | QQVRERNLNP | 
    589:
    KAACLKRREE | EKVSSEPPPL | SLAGPHPGMG | DTANHMGQM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat TCF-4
    Cat.:
    E1408h
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    96T
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    ELISA Kit for Rat TCF-4
    MSDS:
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    ELISA Kit for Rat TCF-4
    Cat.:
    E1408d
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat TCF-4
    Cat.:
    E1408m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat TCF-4
    Cat.:
    E1408r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat TCF-4
    Cat.:
    U1408h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TCF-4
    Cat.:
    U1408r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TCF-4
    Cat.:
    U1408d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TCF-4
    Cat.:
    U1408m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat TCF-4
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Rat TCF-4
    Cat.:
    P1408Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat TCF-4
    Cat.:
    P1408Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat TCF-4
    Polyclonal Antibody for Rat TCF-4
    Polyclonal Antibody for Rat TCF-4
    Cat.:
    P1408Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat TCF-4
    Monoclonal Antibody for Rat TCF-4
    Monoclonal Antibody for Rat TCF-4
    Monoclonal Antibody for Rat TCF-4
    Monoclonal Antibody for Rat TCF-4
    Protein for Rat TCF-4
    Protein for Rat TCF-4
    Protein for Rat TCF-4
    Protein for Rat TCF-4
    Protein for Rat TCF-4

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    References
    1. 1.
      "Identification and analysis of a novel helix-loop-helix transcription factor-encoding gene from Rat forebrain."
      Diaz M.I. , Lopez J. , Padilla S. , Madrazo J.A. , Capo D. , Cabrero N. , Felix C. , Ossorio J. , Olmeda Y. , Lugo D.I.
      Submitted (1999-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Forebrain.
    2. 2.
      "Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer."
      Yoon S.O. , Chikaraishi D.M.
      J. Biol. Chem.269:18453-18462(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 162-589 (ISOFORMS 1 AND 2)
      strain: New England Deaconess Hospital.
      tissue: Adrenal medulla.
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